@inproceedings{306890dcceef4067bad3114c3101806c,
title = "Conditioned medium mediated immune protection in In Vitro model of endogenous neurotoxin N-methyl-salsolinol in an astrocyte-dependent manner",
abstract = "Parkinson{\textquoteright}s Disease (PD) is the second largest neurodegeneration disease in the world, and the etiology of PD is unclear now. Enormous studies focus on the neuroinflammation and innate and adaptive immune system in the pathology of PD. In this study, we used endogenous neurotoxin 1(R),2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline-(N-methyl-salsolinol, NMSal)-treated cocultures of dopaminergic neuron SH-SY5Y cells and astrocytomas U87 cells for 24 hours and then reused this 24-hours-old medium to culture human monocyte THP1 cells for another 24 hours and studied the role of this conditioned medium on THP1 cells. We found 24-hours-old medium-protected monocyte THP1 cells from NMSal-mediated apoptosis in an astrocyte U87 cells-dependent manner.",
author = "Wang, {Fu Li} and Wang, {Xiang Han} and Fan Zeng and Hong Qing and Deng, {Yu Lin}",
note = "Publisher Copyright: {\textcopyright} 2015 Taylor & Francis Group, London.; Proceedings of the 2014 International Conference on Medicine Sciences and Bioengineering, ICMSB 2014 ; Conference date: 16-08-2014 Through 17-08-2014",
year = "2015",
doi = "10.1201/b18418-39",
language = "English",
series = "Medicine Sciences and Bioengineering - Proceedings of the 2014 International Conference on Medicine Sciences and Bioengineering, ICMSB 2014",
publisher = "CRC Press/Balkema",
pages = "199--202",
editor = "Mings Wang",
booktitle = "Medicine Sciences and Bioengineering - Proceedings of the 2014 International Conference on Medicine Sciences and Bioengineering, ICMSB 2014",
}
