Comparison of antileukemic immunity mediated by dendritic cells derived from multidrug resistant leukemia K562/A02 cells and sensitive K562 cells

Yan Ming Zhang, Lian Sheng Zhang*, Yu Fang Zhang, Ye Chai, Liang Cai Yi, Fei Xue Song

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

摘要

In summary, this study indicates that functional DCs can be differentiated from MDR K562/A02 cells and effectively generate a P-gp-specific antileukemic immune response. If a DC based vaccine loaded with P-gp or transferred by mdr1 gene is designed, it maybe provide a novel and promising immunotherapeutic strategy to overcome MDR leukemia in the future.

源语言英语
页(从-至)595-597
页数3
期刊Chinese Medical Journal
118
7
出版状态已出版 - 5 4月 2005
已对外发布

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