TY - JOUR
T1 - Cembranoid diterpenes from soft coral Sinularia sp.
AU - Lv, Fang
AU - Wang, Xianjie
AU - Dai, Rongji
AU - Deng, Yulin
PY - 2010/1
Y1 - 2010/1
N2 - A soft coral Sinularia sp., collected from the South China Sea, was selected to investigate the bioactive and chemical constituents. The EtOAc fraction were isolated by repeatedly silica gel and Sephadex LH-20 column chromatography to obtain lobophytolide A (1), 3-dehydroxylpresinularolide B (2), sarcophine (3), 3β-acetoxyisolobophytolide (4), Crassocolide D (5), (3E, 7E, 11E)-6-acetoxy-3,7,11,15(17)-cembratrien-16,14-olide (6). The structures of compounds 1-6 were determined on the basis of spectroscopic data analysis. All compounds were tested against a small panel of human tumor cell lines. And these compounds were obtained for the first time from this coral.
AB - A soft coral Sinularia sp., collected from the South China Sea, was selected to investigate the bioactive and chemical constituents. The EtOAc fraction were isolated by repeatedly silica gel and Sephadex LH-20 column chromatography to obtain lobophytolide A (1), 3-dehydroxylpresinularolide B (2), sarcophine (3), 3β-acetoxyisolobophytolide (4), Crassocolide D (5), (3E, 7E, 11E)-6-acetoxy-3,7,11,15(17)-cembratrien-16,14-olide (6). The structures of compounds 1-6 were determined on the basis of spectroscopic data analysis. All compounds were tested against a small panel of human tumor cell lines. And these compounds were obtained for the first time from this coral.
KW - Bioactivity
KW - Cembranoid diterpene
KW - Chemical structure
KW - Sinularia sp.
UR - http://www.scopus.com/inward/record.url?scp=77951262061&partnerID=8YFLogxK
U2 - 10.4268/cjcmm20100212
DO - 10.4268/cjcmm20100212
M3 - Article
C2 - 20394288
AN - SCOPUS:77951262061
SN - 1001-5302
VL - 35
SP - 177
EP - 179
JO - Zhongguo Zhongyao Zazhi
JF - Zhongguo Zhongyao Zazhi
IS - 2
ER -