Cembranoid diterpenes from soft coral Sinularia sp.

Fang Lv; Xianjie Wang; Rongji Dai; Yulin Deng

doi:10.4268/cjcmm20100212

Cembranoid diterpenes from soft coral Sinularia sp.

Fang Lv^*, Xianjie Wang, Rongji Dai, Yulin Deng

^*此作品的通讯作者

Qingdao University of Science and Technology

科研成果: 期刊稿件 › 文章 › 同行评审

摘要

A soft coral Sinularia sp., collected from the South China Sea, was selected to investigate the bioactive and chemical constituents. The EtOAc fraction were isolated by repeatedly silica gel and Sephadex LH-20 column chromatography to obtain lobophytolide A (1), 3-dehydroxylpresinularolide B (2), sarcophine (3), 3β-acetoxyisolobophytolide (4), Crassocolide D (5), (3E, 7E, 11E)-6-acetoxy-3,7,11,15(17)-cembratrien-16,14-olide (6). The structures of compounds 1-6 were determined on the basis of spectroscopic data analysis. All compounds were tested against a small panel of human tumor cell lines. And these compounds were obtained for the first time from this coral.

源语言	英语
页（从-至）	177-179
页数	3
期刊	Zhongguo Zhongyao Zazhi
卷	35
期	2
DOI	https://doi.org/10.4268/cjcmm20100212
出版状态	已出版 - 1月 2010

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10.4268/cjcmm20100212

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Lv, F., Wang, X., Dai, R., & Deng, Y. (2010). Cembranoid diterpenes from soft coral Sinularia sp. Zhongguo Zhongyao Zazhi, 35(2), 177-179. https://doi.org/10.4268/cjcmm20100212

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title = "Cembranoid diterpenes from soft coral Sinularia sp.",

abstract = "A soft coral Sinularia sp., collected from the South China Sea, was selected to investigate the bioactive and chemical constituents. The EtOAc fraction were isolated by repeatedly silica gel and Sephadex LH-20 column chromatography to obtain lobophytolide A (1), 3-dehydroxylpresinularolide B (2), sarcophine (3), 3β-acetoxyisolobophytolide (4), Crassocolide D (5), (3E, 7E, 11E)-6-acetoxy-3,7,11,15(17)-cembratrien-16,14-olide (6). The structures of compounds 1-6 were determined on the basis of spectroscopic data analysis. All compounds were tested against a small panel of human tumor cell lines. And these compounds were obtained for the first time from this coral.",

keywords = "Bioactivity, Cembranoid diterpene, Chemical structure, Sinularia sp.",

author = "Fang Lv and Xianjie Wang and Rongji Dai and Yulin Deng",

year = "2010",

month = jan,

doi = "10.4268/cjcmm20100212",

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AU - Lv, Fang

AU - Wang, Xianjie

AU - Dai, Rongji

AU - Deng, Yulin

PY - 2010/1

Y1 - 2010/1

N2 - A soft coral Sinularia sp., collected from the South China Sea, was selected to investigate the bioactive and chemical constituents. The EtOAc fraction were isolated by repeatedly silica gel and Sephadex LH-20 column chromatography to obtain lobophytolide A (1), 3-dehydroxylpresinularolide B (2), sarcophine (3), 3β-acetoxyisolobophytolide (4), Crassocolide D (5), (3E, 7E, 11E)-6-acetoxy-3,7,11,15(17)-cembratrien-16,14-olide (6). The structures of compounds 1-6 were determined on the basis of spectroscopic data analysis. All compounds were tested against a small panel of human tumor cell lines. And these compounds were obtained for the first time from this coral.

AB - A soft coral Sinularia sp., collected from the South China Sea, was selected to investigate the bioactive and chemical constituents. The EtOAc fraction were isolated by repeatedly silica gel and Sephadex LH-20 column chromatography to obtain lobophytolide A (1), 3-dehydroxylpresinularolide B (2), sarcophine (3), 3β-acetoxyisolobophytolide (4), Crassocolide D (5), (3E, 7E, 11E)-6-acetoxy-3,7,11,15(17)-cembratrien-16,14-olide (6). The structures of compounds 1-6 were determined on the basis of spectroscopic data analysis. All compounds were tested against a small panel of human tumor cell lines. And these compounds were obtained for the first time from this coral.

KW - Bioactivity

KW - Cembranoid diterpene

KW - Chemical structure

KW - Sinularia sp.

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Cembranoid diterpenes from soft coral Sinularia sp.

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