@article{a6568c714c754b14bd35b7cfe788b3b0,
title = "Catalytic asymmetric construction of spiro(γ-butyrolactam-γ- butyrolactone) moieties through sequential reactions of cyclic imino esters with Morita-Baylis-Hillman bromides",
abstract = "Spiro(γ-butyrolactam-γ-butyrolactone): A route to enantioenriched spiro(γ-butyrolactam-γ-butyrolactone) compounds, a valuable motif for drug discovery, was developed by use of a highly efficient copper(I)/TF-BiphamPhos-catalyzed tandem Michael addition-elimination of homoserine lactone derived cyclic imino esters with Morita-Baylis-Hillman (MBH) bromides, followed by treatment with para-toluenesulfonic acid (see scheme).",
keywords = "asymmetric catalysis, bromides, diastereoselectivity, enantioselectivity, imino esters, spiro compounds",
author = "Teng, {Huai Long} and He Huang and Wang, {Chun Jiang}",
year = "2012",
month = oct,
day = "1",
doi = "10.1002/chem.201201475",
language = "English",
volume = "18",
pages = "12614--12618",
journal = "Chemistry - A European Journal",
issn = "0947-6539",
publisher = "Wiley-VCH Verlag",
number = "40",
}