Calcium channel blockers and Alzheimer's disease

Yi Tan; Yulin Deng; Hong Qing

doi:10.3969/j.issn.1673-5374.2012.02.010

Calcium channel blockers and Alzheimer's disease

Yi Tan, Yulin Deng, Hong Qing^*

^*此作品的通讯作者

医学技术学院

Beijing Institute of Technology

科研成果: 期刊稿件 › 文章 › 同行评审

21 引用（Scopus）

摘要

Alzheimer's disease is characterized by two pathological hallmarks: amyloid plaques and neurofibrillary tangles. In addition, calcium homeostasis is disrupted in the course of human aging. Recent research shows that dense plaques can cause functional alteration of calcium signals in mice with Alzheimer's disease. Calcium channel blockers are effective therapeutics for treating Alzheimer's disease. This review provides an overview of the current research of calcium channel blockers involved in Alzheimer's disease therapy.

源语言	英语
页（从-至）	137-140
页数	4
期刊	Neural Regeneration Research
卷	7
期	2
DOI	https://doi.org/10.3969/j.issn.1673-5374.2012.02.010
出版状态	已出版 - 1月 2012

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KW - Alzheimer's disease pathogenesis

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KW - Calcium homeostasis

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Calcium channel blockers and Alzheimer's disease

摘要

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