Base-catalyzed one-pot tandem reaction: An effective strategy for the synthesis of pyrazolo[3,4-d]pyrimidinone derivatives

Ming Xing Liu, Jia Rong Li, Kai Zheng, Huan Yao, Qi Zhang, Da Xin Shi*

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

11 引用 (Scopus)

摘要

An effective one-pot multicomponent synthesis of pyrazolo[3,4-d]pyrimidinone derivatives through the tandem heterocyclization of hydrazine, methylenemalononitrile and aldehyde has been developed. This highly effective method includes nucleophilic addition, heterocyclization, substitution, intramolecular Pinner, Dimroth rearrangement and dehydroaromatization.

源语言英语
文章编号27010
页(从-至)7658-7662
页数5
期刊Tetrahedron
71
40
DOI
出版状态已出版 - 7 10月 2015

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