Automated bubble-based assembly of cell-laden microgels into vascular-like microtubes

科研成果: 书/报告/会议事项章节会议稿件同行评审

4 引用 (Scopus)

摘要

Fabrication of artificial blood vessels in micro scale significantly benefits the regeneration of functional human vascular networks. In this paper, we develop an efficient multi-microrobotic system with an innovative motorized sample holder (MSH) and two manipulators. Air is injected into the solution through a glass pipette fixed on one manipulator to create bubbles. These bubbles conduct a regular rising movement, which is utilized to assemble the 2D ring-shaped microgels fabricated in a simple micro fluidic device. With this novel bubble-based method and the robotic system, we achieve the automation of the assembly. A 1.2 mm long vascular-like microtube with an outer diameter of 200 μm is fabricated. The whole process of the bubble-based assembly is visually observed and analyzed with side view. Key parameters are characterized to improve the assembly. Results show that the automated bubble-based assembly success rate is 100% and average time cost of assembling every microgel is as low as 3.25s.

源语言英语
主期刊名IROS Hamburg 2015 - Conference Digest
主期刊副标题IEEE/RSJ International Conference on Intelligent Robots and Systems
出版商Institute of Electrical and Electronics Engineers Inc.
798-803
页数6
ISBN(电子版)9781479999941
DOI
出版状态已出版 - 11 12月 2015
活动IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2015 - Hamburg, 德国
期限: 28 9月 20152 10月 2015

出版系列

姓名IEEE International Conference on Intelligent Robots and Systems
2015-December
ISSN(印刷版)2153-0858
ISSN(电子版)2153-0866

会议

会议IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2015
国家/地区德国
Hamburg
时期28/09/152/10/15

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