Asymmetric reactions catalyzed by chiral titanium complexes

This presentation reviewed some of our recent progress in asymmetric reactions catalyzed by chiral Ti(IV) complexes, including asymmetric oxa-Diels-Alder reaction(up to 99%ee), asymmetric oxidation of sulfides for sulfoxides (up to 96% ee), enantioselective silylcyanation of aldehydes (up to 87% ee) and ketones (up to 69% ee). The influence of ligand structure, substrate, amount of catalyst, counter ion, solvent, temperature, and other conditions on the reactivity and selectivity were discussed. Some mechanistic insights were also presented.