摘要
This chapter introduces the aptamers for targeted therapy. Aptamers show promising efficacy and safety in four types of clinical studies of ophthalmopathy, blood coagulation, inflammation, and cancer, and there are increasing numbers of evidences to prove the clinical application potential of aptamers. To date, more than a dozen aptamers have entered clinical trials as therapeutic agents for targeted therapy. This chapter introduces their pharmacological development and optimization processes and reviews potential treatment of diseases.
源语言 | 英语 |
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主期刊名 | Aptamers for Medical Applications |
主期刊副标题 | From Diagnosis to Therapeutics |
出版商 | Springer Singapore |
页 | 129-178 |
页数 | 50 |
ISBN(电子版) | 9789813348387 |
ISBN(印刷版) | 9789813348370 |
DOI | |
出版状态 | 已出版 - 1 1月 2021 |
已对外发布 | 是 |