Anti-biofouling function of amorphous nano-Ta₂O₅ coating for VO₂-based intelligent windows

From environmental and health perspectives, the acquisition of a surface anti-biofouling property holds important significance for the usability of VO₂ intelligent windows. Herein, we firstly deposited amorphous Ta₂O₅ nanoparticles on VO₂ film by the magnetron sputtering method. It was found that the amorphous nano-Ta₂O₅ coating possessed a favorable anti-biofouling capability against Pseudomonas aeruginosa as an environmental microorganism model, behind which lay the mechanism that the amorphous nano-Ta₂O₅ could interrupt the microbial membrane electron transport chain and significantly elevate the intracellular reactive oxygen species (ROS) level. A plausible relationship was established between the anti-biofouling activity and physicochemical nature of amorphous Ta₂O₅ nanoparticles from the perspective of defect chemistry. ROS-induced oxidative damage gave rise to microbial viability loss. In addition, the amorphous nano-Ta₂O₅ coating can endow VO₂ with favorable cytocompatibility with human skin fibroblasts. This study may provide new insights into understanding the anti-biofouling and antimicrobial actions of amorphous transition metal oxide nanoparticles, which is conducive to expanding their potential applications in environmental fields.