An electrophilic thiocyanation/ipso-cyclization leading to spirocyclohexadienones

Zhihua Qiao, Chukai Shao, Yong Gao, Kun Liang, Hongquan Yin, Fu Xue Chen*

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

8 引用 (Scopus)

摘要

A Lewis acid-catalyzed cyclization of N-(p-methoxyphenyl)-3-phenylpropionamide with N-thiocyanosuccinimide has been accomplished under mild conditions. Thus, a series of thiocyanato-containing spirocyclohexadienones was obtained in moderate to excellent yields with a good functional group tolerance and a wide range of substrates. It provides an alternative approach for the synthesis of functionalized spirocyclohexadienones.

源语言英语
文章编号153875
期刊Tetrahedron Letters
100
DOI
出版状态已出版 - 22 6月 2022

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