TY - JOUR
T1 - Advancements in Testing Strategies for COVID‐19
AU - Asghar, Rabia
AU - Rasheed, Madiha
AU - Hassan, Jalees Ul
AU - Rafique, Mohsin
AU - Khan, Mashooq
AU - Deng, Yulin
N1 - Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/6
Y1 - 2022/6
N2 - The SARS‐CoV‐2 coronavirus, also known as the disease‐causing agent for COVID‐19, is a virulent pathogen that may infect people and certain animals. The global spread of COVID‐19 and its emerging variation necessitates the development of rapid, reliable, simple, and low‐cost diagnostic tools. Many methodologies and devices have been developed for the highly sensitive, selec-tive, cost‐effective, and rapid diagnosis of COVID‐19. This review organizes the diagnosis platforms into four groups: imaging, molecular‐based detection, serological testing, and biosensors. Each plat-form’s principle, advancement, utilization, and challenges for monitoring SARS‐CoV‐2 are dis-cussed in detail. In addition, an overview of the impact of variants on detection, commercially available kits, and readout signal analysis has been presented. This review will expand our understand-ing of developing advanced diagnostic approaches to evolve into susceptible, precise, and repro-ducible technologies to combat any future outbreak.
AB - The SARS‐CoV‐2 coronavirus, also known as the disease‐causing agent for COVID‐19, is a virulent pathogen that may infect people and certain animals. The global spread of COVID‐19 and its emerging variation necessitates the development of rapid, reliable, simple, and low‐cost diagnostic tools. Many methodologies and devices have been developed for the highly sensitive, selec-tive, cost‐effective, and rapid diagnosis of COVID‐19. This review organizes the diagnosis platforms into four groups: imaging, molecular‐based detection, serological testing, and biosensors. Each plat-form’s principle, advancement, utilization, and challenges for monitoring SARS‐CoV‐2 are dis-cussed in detail. In addition, an overview of the impact of variants on detection, commercially available kits, and readout signal analysis has been presented. This review will expand our understand-ing of developing advanced diagnostic approaches to evolve into susceptible, precise, and repro-ducible technologies to combat any future outbreak.
KW - SARS‐CoV‐2
KW - coronavirus
KW - diagnosis
KW - immunoassays
KW - variants
UR - http://www.scopus.com/inward/record.url?scp=85132603662&partnerID=8YFLogxK
U2 - 10.3390/bios12060410
DO - 10.3390/bios12060410
M3 - Review article
C2 - 35735558
AN - SCOPUS:85132603662
SN - 2079-6374
VL - 12
JO - Biosensors
JF - Biosensors
IS - 6
M1 - 410
ER -