@article{dfeb1eaddf0b424b99fc167847fa1836,
title = "A Mild Multi-Component Reaction for the Synthesis of 4,5-Disubstituted 1 H -1,2,3-Triazoles from Phosphonium Salts, Aldehydes, and Sodium Azide",
abstract = "A mild and metal-free multi-component reaction to synthesize 4,5-disubstituted 1 H -1,2,3-triazoles from phosphonium salts, aldehydes, and sodium azide is described. The process undergoes an organocatalyzed coupling of formyl group with phosphonium to form a key intermediate, olefinic phosphonium salt, which is followed by the [3+2] cycloaddition of the azide to the activated alkene. A series of representative 4,5-disubstituted 1 H -1,2,3-triazoles were prepared.",
keywords = "cycloaddition, multicomponent reaction, organic catalyst, phosphonium salt, triazole",
author = "Wu, {Guang Long} and Wu, {Qin Pei}",
note = "Publisher Copyright: {\textcopyright} Georg Thieme Verlag Stuttgart New York.",
year = "2018",
month = jul,
day = "17",
doi = "10.1055/s-0037-1609720",
language = "English",
volume = "50",
pages = "2768--2774",
journal = "Synthesis",
issn = "0039-7881",
publisher = "Georg Thieme Verlag",
number = "14",
}