A highly selective wavelength-ratiometric and colorimetric probe for cysteine

Xiaodan Zeng; Xiaoling Zhang; Baocun Zhu; Hongying Jia; Yamin Li

doi:10.1016/j.dyepig.2011.10.013

A highly selective wavelength-ratiometric and colorimetric probe for cysteine

Xiaodan Zeng, Xiaoling Zhang^*, Baocun Zhu, Hongying Jia, Yamin Li

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化学与化工学院

科研成果: 期刊稿件 › 文章 › 同行评审

35 引用（Scopus）

摘要

Based on the nucleophilic aromatic substitution reaction mechanism, a new highly selective probe for cysteine (Cys), N-butyl-4-bromo-3-nitro-1,8- naphthalimide (1), was designed and synthesized. The probe displayed a remarkable (58 nm) red-shift in the absorption spectra and the color changes from colorless to yellow upon reaction with Cys. The probe could detect Cys quantitatively in the range of 0-0.9 mM by both normal and ratiometric absorption spectrometry methods. Moreover, 1 could also serve as a "naked-eye" probe for Cys with a minimum detectable concentration of approximately 50 μM.

源语言	英语
页（从-至）	10-15
页数	6
期刊	Dyes and Pigments
卷	94
期	1
DOI	https://doi.org/10.1016/j.dyepig.2011.10.013
出版状态	已出版 - 7月 2012

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10.1016/j.dyepig.2011.10.013

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Zeng, X., Zhang, X., Zhu, B., Jia, H., & Li, Y. (2012). A highly selective wavelength-ratiometric and colorimetric probe for cysteine. Dyes and Pigments, 94(1), 10-15. https://doi.org/10.1016/j.dyepig.2011.10.013

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title = "A highly selective wavelength-ratiometric and colorimetric probe for cysteine",

abstract = "Based on the nucleophilic aromatic substitution reaction mechanism, a new highly selective probe for cysteine (Cys), N-butyl-4-bromo-3-nitro-1,8- naphthalimide (1), was designed and synthesized. The probe displayed a remarkable (58 nm) red-shift in the absorption spectra and the color changes from colorless to yellow upon reaction with Cys. The probe could detect Cys quantitatively in the range of 0-0.9 mM by both normal and ratiometric absorption spectrometry methods. Moreover, 1 could also serve as a {"}naked-eye{"} probe for Cys with a minimum detectable concentration of approximately 50 μM.",

keywords = "Colorimetric, Cysteine, Naphthalimide, Nucleophilic aromatic substitution, Probe, Ratiometric",

author = "Xiaodan Zeng and Xiaoling Zhang and Baocun Zhu and Hongying Jia and Yamin Li",

year = "2012",

month = jul,

doi = "10.1016/j.dyepig.2011.10.013",

language = "English",

volume = "94",

pages = "10--15",

journal = "Dyes and Pigments",

issn = "0143-7208",

publisher = "Elsevier B.V.",

number = "1",

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TY - JOUR

T1 - A highly selective wavelength-ratiometric and colorimetric probe for cysteine

AU - Zeng, Xiaodan

AU - Zhang, Xiaoling

AU - Zhu, Baocun

AU - Jia, Hongying

AU - Li, Yamin

PY - 2012/7

Y1 - 2012/7

N2 - Based on the nucleophilic aromatic substitution reaction mechanism, a new highly selective probe for cysteine (Cys), N-butyl-4-bromo-3-nitro-1,8- naphthalimide (1), was designed and synthesized. The probe displayed a remarkable (58 nm) red-shift in the absorption spectra and the color changes from colorless to yellow upon reaction with Cys. The probe could detect Cys quantitatively in the range of 0-0.9 mM by both normal and ratiometric absorption spectrometry methods. Moreover, 1 could also serve as a "naked-eye" probe for Cys with a minimum detectable concentration of approximately 50 μM.

AB - Based on the nucleophilic aromatic substitution reaction mechanism, a new highly selective probe for cysteine (Cys), N-butyl-4-bromo-3-nitro-1,8- naphthalimide (1), was designed and synthesized. The probe displayed a remarkable (58 nm) red-shift in the absorption spectra and the color changes from colorless to yellow upon reaction with Cys. The probe could detect Cys quantitatively in the range of 0-0.9 mM by both normal and ratiometric absorption spectrometry methods. Moreover, 1 could also serve as a "naked-eye" probe for Cys with a minimum detectable concentration of approximately 50 μM.

KW - Colorimetric

KW - Cysteine

KW - Naphthalimide

KW - Nucleophilic aromatic substitution

KW - Probe

KW - Ratiometric

UR - http://www.scopus.com/inward/record.url?scp=84055217360&partnerID=8YFLogxK

U2 - 10.1016/j.dyepig.2011.10.013

DO - 10.1016/j.dyepig.2011.10.013

M3 - Article

AN - SCOPUS:84055217360

SN - 0143-7208

VL - 94

SP - 10

EP - 15

JO - Dyes and Pigments

JF - Dyes and Pigments

IS - 1

ER -

A highly selective wavelength-ratiometric and colorimetric probe for cysteine

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