A convenient four-component one-pot strategy toward the synthesis of pyrazolo[3,4-d]pyrimidines

Mingxing Liu, Jiarong Li, Hongxin Chai, Kai Zhang, Deli Yang, Qi Zhang, Daxin Shi*

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

7 引用 (Scopus)

摘要

An efficient one-pot synthesis of pyrazolo[3,4-d]pyrimidine derivatives by the four-component condensation of hydrazines, methylenemalononitriles, aldehydes and alcohols has been developed via two different reaction pathways. The structures of target products were characterized by IR spectroscopy, NMR (1H and 13C) spectroscopy and HRMS (ESI) spectrometry. The crystal structure of 4-ethoxy-6-(2-nitrophenyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine was determined by single crystal X-ray diffraction.

源语言英语
页(从-至)2125-2131
页数7
期刊Beilstein Journal of Organic Chemistry
11
DOI
出版状态已出版 - 6 11月 2015

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