北京大学化学与化工学院博士,美国莱斯大学博士后,主持国家自然科学基金青年项目,北理工青年教师学术启动计划和北京理工大学科技创新计划科研基地科技支撑专项计划。在国内外学术刊物上发表学术论文30余篇,包括J. Am. Chem. Soc., Chem. Sci.等。
我的研究兴趣主要集中在化学与生命科学的交叉领域,旨在通过发展化学工具探测和调节生命过程,揭示生物事件的发生发展规律,为疾病的治疗提供新思路。包括:1)发展低能量光可活化荧光探针监测细胞通讯动力学;2)发展阴离子配体靶向性治疗癌症;3)发展不含重金属的光敏剂用于癌症的光动力治疗。
2012.09-2017.07 北京大学,化学专业,理学博士
2008.09-2012.07 武汉大学,药学专业,理学学士
2020.12至今 北京理工大学化学与化工学院,预聘副教授,博士生导师
2017.08-2020.06 美国莱斯大学,化学院,博士后研究员
迄今在国内外学术刊物及会议上发表学术论文30篇,其中SCI收录26篇,EI收录14篇,两项美国专利正在审批,代表性论文如下:
(1)Juan Tang, # Michael Robichaux, # Kuan-Lin Wu, Jingqi Pei, Nhung T. Nguyen, Yubin Zhou, Theodore G. Wensel*, and Han Xiao*, Single-Atom Fluorescence Switch: A General Approach towards Visible Light-Activated Dyes for Biological Imaging, J. Am. Chem. Soc., 2019, 141, 37, 14699 (# contributed equally). Highlighted by JACS Spotlight [Link], and C&EN [Link]. Featured in Rice News [Link], and ScienceDaily [Link]
(2)Juan Tang, # Lushun Wang, # Axel Loredo, Carson Cole, and Han Xiao*, Single-Atom Replacement as a General Approach Towards Visible-Light/Near-Infrared Heavy-Atom-Free Photosensitizers for Photodynamic Therapy, Chem. Sci., 2020, 11, 6701 (# contributed equally). Included in 2020 Chemical Science HOT Article Collection [Link], Featured in Rice News [Link] Phys.org [Link]
(3)Juan Tang, # Chenfei Yu, Axel Loredo, Yuda Chen, and Han Xiao*, Site-Specific Incorporation of a Photoactivatable Fluorescent Amino Acid, ChemBioChem, 2020, 22, 501
(4)Juan Tang, Hao-Yan Yin, Jun-Long Zhang*, A luminescent aluminium salen complex allows for monitoring dynamic vesicle trafficking from the Golgi apparatus to lysosomes in living cells, Chem. Sci., 2018, 9, 1931
(5)Juan Tang, Yuan-Bo Cai, Jing Jing and Jun-Long Zhang*, Unravelling the Correlation between Metal Induced Aggregation and Cellular Uptake/Subcellular Localization of Znsalen: An Overlooked Rule for Design of Luminescent Metal Probes, Chem. Sci., 2015, 6, 238