Ultraweak bioluminescence imaging and image processing

Tianming Chen*, Susheng Wang, Qin Li, Xin Yu

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Citations (Scopus)

Abstract

A photon counting imaging system which can detect emission down to the order of 1 counts cm -2 sec -1 (at the photocathode) has been developed, and it has been used to obtain the ultraweak bioluminescence images of a living Kunming mouse. In this paper, we give statistical analysis for calculation of the photon distribution in images obtained, and we use Chi-square (χ 2) statistic to get signal and noise distribution to process these images. It has been proved that the imaging system has the ability in detecting ultraweak bioluminescence of animals, and the statistical method for image processing can effectively increase the signal/noise ratio and improve the image quality.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsWilliam G. Frederick, Junhong Su, Marc Wigdor
Pages276-281
Number of pages6
Publication statusPublished - 1996
EventDetectors, Focal Plane Arrays, and Applications - Beijing, China
Duration: 4 Nov 19965 Nov 1996

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume2894
ISSN (Print)0277-786X

Conference

ConferenceDetectors, Focal Plane Arrays, and Applications
CityBeijing, China
Period4/11/965/11/96

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