Ti3C2 MXene as a novel substrate provides rapid differentiation and quantitation of glycan isomers with LDI-MS

Yuming Jiang; Jie Sun; Yi Cui; Huihui Liu; Xiaoyong Zhang; Yurong Jiang; Zongxiu Nie

doi:10.1039/c9cc04467a

Ti₃C₂ MXene as a novel substrate provides rapid differentiation and quantitation of glycan isomers with LDI-MS

Yuming Jiang^*, Jie Sun, Yi Cui, Huihui Liu, Xiaoyong Zhang, Yurong Jiang, Zongxiu Nie

^*Corresponding author for this work

School of Optics and Photonics

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

Here we report Ti₃C₂ MXene assisted LDI-LIFT-TOF/TOF for robust differentiation and relative quantitation of glycan isomers that differ in composition, connectivity and configuration. The improved sensitivity and background-free properties of this substrate combined with the special fragment profile produced by LDI-LIFT-TOF/TOF open a new door for nanomaterial assisted glycan structual analysis.

Original language	English
Pages (from-to)	10619-10622
Number of pages	4
Journal	Chemical Communications
Volume	55
Issue number	71
DOIs	https://doi.org/10.1039/c9cc04467a
Publication status	Published - 2019

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abstract = "Here we report Ti3C2 MXene assisted LDI-LIFT-TOF/TOF for robust differentiation and relative quantitation of glycan isomers that differ in composition, connectivity and configuration. The improved sensitivity and background-free properties of this substrate combined with the special fragment profile produced by LDI-LIFT-TOF/TOF open a new door for nanomaterial assisted glycan structual analysis.",

author = "Yuming Jiang and Jie Sun and Yi Cui and Huihui Liu and Xiaoyong Zhang and Yurong Jiang and Zongxiu Nie",

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AU - Jiang, Yuming

AU - Sun, Jie

AU - Cui, Yi

AU - Liu, Huihui

AU - Zhang, Xiaoyong

AU - Jiang, Yurong

AU - Nie, Zongxiu

N1 - Publisher Copyright: This journal is © The Royal Society of Chemistry.

PY - 2019

Y1 - 2019

N2 - Here we report Ti3C2 MXene assisted LDI-LIFT-TOF/TOF for robust differentiation and relative quantitation of glycan isomers that differ in composition, connectivity and configuration. The improved sensitivity and background-free properties of this substrate combined with the special fragment profile produced by LDI-LIFT-TOF/TOF open a new door for nanomaterial assisted glycan structual analysis.

AB - Here we report Ti3C2 MXene assisted LDI-LIFT-TOF/TOF for robust differentiation and relative quantitation of glycan isomers that differ in composition, connectivity and configuration. The improved sensitivity and background-free properties of this substrate combined with the special fragment profile produced by LDI-LIFT-TOF/TOF open a new door for nanomaterial assisted glycan structual analysis.

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U2 - 10.1039/c9cc04467a

DO - 10.1039/c9cc04467a

M3 - Article

C2 - 31428752

AN - SCOPUS:85071713433

SN - 1359-7345

VL - 55

SP - 10619

EP - 10622

JO - Chemical Communications

JF - Chemical Communications

IS - 71

ER -

Ti₃C₂ MXene as a novel substrate provides rapid differentiation and quantitation of glycan isomers with LDI-MS

Abstract

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