Three-Dimensionally Printed Bionic Hydroxyapatite (HAp) Ceramic Scaffolds with Different Structures and Porosities: Strength, Biocompatibility, and Biomedical Application Potential

Peng Zhang, Qing Zhou, Rujie He*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Plum Print visual indicator of research metrics
  • Captures
    • Readers: 3
  • Mentions
    • News Mentions: 1
see details

Abstract

Bionic bioceramic scaffolds are essential for achieving excellent implant properties and biocompatible behavior. In this study, inspired by the microstructure of natural bone, bionic hydroxyapatite (HAp) ceramic scaffolds with different structures (body-centered cubic (BCC), face-centered cubic (FCC), and gyroid Triply Periodic Minimal Surfaces (TPMSs)) and porosities (80 vol.%, 60 vol.%, and 40 vol.%) were designed, 3D-printed, and characterized. The effects of structure and porosity on the morphology, mechanical properties, and in vitro biocompatibility properties of the HAp scaffolds were studied and compared with each other. Interestingly, the HAp scaffold with a porosity of 80 vol.% and a TPMS structure had the best combination of compressive strength and in vitro biocompatibility, and demonstrated a great biomedical application potential for bone repair. We hope this study can provide a reference for the application and development of HAp scaffolds in the field of bone repair engineering.

Original languageEnglish
Article number6092
JournalMaterials
Volume17
Issue number24
DOIs
Publication statusPublished - Dec 2024

Keywords

  • 3D printing
  • biocompatibility
  • hydroxyapatite
  • mechanical properties
  • scaffold

Fingerprint

Dive into the research topics of 'Three-Dimensionally Printed Bionic Hydroxyapatite (HAp) Ceramic Scaffolds with Different Structures and Porosities: Strength, Biocompatibility, and Biomedical Application Potential'. Together they form a unique fingerprint.

Cite this

Zhang, P., Zhou, Q., & He, R. (2024). Three-Dimensionally Printed Bionic Hydroxyapatite (HAp) Ceramic Scaffolds with Different Structures and Porosities: Strength, Biocompatibility, and Biomedical Application Potential. Materials, 17(24), Article 6092. https://doi.org/10.3390/ma17246092