Theoretical analysis on particle manipulation of the optical tweezers arrays system

Li Qin*, Feng Wanli, Wang Chu, Cao Qun, Hu Xiaoming, Sha Dingguo, Lin Jiaming, Zhu Dejun

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In biological scientific research, separating biological macromolecules or cells in liquid is always a challenging job. Optical tweezers have been a valuable research tool since their invention in the 1980s. One of the most important developments in optical tweezers in recent years has been the creation of two-dimensional arrays of optical traps. In this paper, a method based on interference is discussed to form the gradient laser fields, which may cause spatial modulation of the concentration of particles. The parameters related with the optical tweezers array are discussed in detail and simulated by Matlab software to show the impact factor of the important parameters for the concentration distribution of the particles. The spatial redistribution of particles in a laser interference field could be also predicted according the theoretical analysis.

Original languageEnglish
Title of host publicationFifth International Conference on Photonics and Imaging in Biology and Medicine
EditionPART 1
DOIs
Publication statusPublished - 2007
EventFifth International Conference on Photonics and Imaging in Biology and Medicine - Wuhan, China
Duration: 1 Sept 20063 Sept 2006

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
NumberPART 1
Volume6534
ISSN (Print)1605-7422

Conference

ConferenceFifth International Conference on Photonics and Imaging in Biology and Medicine
Country/TerritoryChina
CityWuhan
Period1/09/063/09/06

Keywords

  • Gradient force
  • Interference
  • Optical tweezers array
  • Spatial modulation

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Qin, L., Wanli, F., Chu, W., Qun, C., Xiaoming, H., Dingguo, S., Jiaming, L., & Dejun, Z. (2007). Theoretical analysis on particle manipulation of the optical tweezers arrays system. In Fifth International Conference on Photonics and Imaging in Biology and Medicine (PART 1 ed.). Article 653415 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6534, No. PART 1). https://doi.org/10.1117/12.741477