The introduction of click chemistry reaction

Click chemistry, which is also called as linkage chemistry, dynamic, combinatorial chemistry or quick linking combinatorial chemistry, describes the reaction that joins molecular fragments as simple, efficient and versatile as clicking a mouse. The two units with specific click structures can be linked by click reaction, no matter what is attached to the structure and only the specific click structures can be joined. It emphasizes the development of new combinatorial chemistries on the basis of the synthesis of efficient and highly selective carbon-heteroatom bond (C-X-C) and effectively prepares molecules with high diversity by these simple reactions. It significantly simplified and promoted the development of synthesis chemistry. Click chemistry has become one of the most useful and attractive synthetic strategy in many fields. In the current chapter, the definition of the click chemistry was explained, the characteristics and types of the click chemistry was introduces, some specific reaction types were focused. Application of click chemistry in different fields and its development were briefly introduced. It is helpful for the whole comprehension of the readers to the characteristics and development of this type reaction.