Abstract
A modified Friedländer conversion of the cyclocondensation of aromatic o-aminonitriles with carbonyl compounds was discovered. Systematic studies reveal that both the new transformation and the classic Friedländer annulation in the presence of ZnCl 2 constitute a pair of divergent reaction, and thecontrolled PDF transformation of this divergent reaction was achieved in the present of bases.
Original language | English |
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Pages (from-to) | 533-542 |
Number of pages | 10 |
Journal | Journal of Heterocyclic Chemistry |
Volume | 49 |
Issue number | 3 |
DOIs | |
Publication status | Published - May 2012 |