The divergent transformations of aromatic o-aminonitrile with carbonyl compound

Jianhong Tang*, Jiarong Li, Lijun Zhang, Shuling Ma, Daxin Shi, Qi Zhang, Liupan Yang, Xiuzhen Wang, Xuan Liu, Change Liu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

A modified Friedländer conversion of the cyclocondensation of aromatic o-aminonitriles with carbonyl compounds was discovered. Systematic studies reveal that both the new transformation and the classic Friedländer annulation in the presence of ZnCl 2 constitute a pair of divergent reaction, and thecontrolled PDF transformation of this divergent reaction was achieved in the present of bases.

Original languageEnglish
Pages (from-to)533-542
Number of pages10
JournalJournal of Heterocyclic Chemistry
Volume49
Issue number3
DOIs
Publication statusPublished - May 2012

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