Abstract
A biocompatible diisocyanate, lysine ethyl ester diisocyanate, was prepared. Afterwards, biodegradable polyurethane (PU) was synthesized by the stepgrowth polymerization of this diisocyanate with hydroxyl terminated poly(ε-caprolactone) in the presence of 1,4-butanediol as a chain-extender. The resulting PU was characterized by GPC, IR and DSC measurements. Its mechanical strength was found to increase with increasing the hard segment content. The PU microfiber meshes with high porosity were obtained by solution electrospinning technique. Their degradation behavior in the PBS and enzymatic solution was also investigated.
Original language | English |
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Pages (from-to) | 25-32 |
Number of pages | 8 |
Journal | Frontiers of Materials Science in China |
Volume | 3 |
Issue number | 1 |
DOIs | |
Publication status | Published - Mar 2009 |
Keywords
- Biodegradability
- L-lysine ethyl ester diisocyanate
- Poly(ε-caprolactone)
- Polyurethane
- Solution electrospinning