Study on the in vitro degradation behavior of pure Mg and WE43 in human bile for 60 days for future usage in biliary

Yang Liu; Shengmin Zheng; Nan Li; Huahu Guo; Yufeng Zheng; Jirun Peng

doi:10.1016/j.matlet.2016.05.042

Study on the in vitro degradation behavior of pure Mg and WE43 in human bile for 60 days for future usage in biliary

Yang Liu, Shengmin Zheng, Nan Li, Huahu Guo, Yufeng Zheng^*, Jirun Peng

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Mg and its alloys have been tested in both bone and blood environment, but the degradation process in human bile have not been reported yet. In this case, commercial pure Mg and WE43 alloy were investigated in human bile to see the corrosion performance as potential biliary stent materials. The results revealed the weight loss of WE43 after 60 days immersion was only 1.87%. Moreover, WE43 performed a superior corrosion resistance to pure Mg, owing to more formation of the secondary reaction product Mg(H₂PO₄)₂. The formation of H₂PO₄^- instead of PO₄^3- may be due to the fact that the compositions in the bile can prevent the formation of PO₄^3- as it is the main composition of gallstone. The much slower corrosion rate of the WE43 alloy in human bile indicated that it may be good candidates as biliary stent materials.

Original language	English
Pages (from-to)	100-103
Number of pages	4
Journal	Materials Letters
Volume	179
DOIs	https://doi.org/10.1016/j.matlet.2016.05.042
Publication status	Published - 15 Sept 2016
Externally published	Yes

Keywords

Corrosion
Human bile
Key words Biomedical magnesium alloy
WE43

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10.1016/j.matlet.2016.05.042

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title = "Study on the in vitro degradation behavior of pure Mg and WE43 in human bile for 60 days for future usage in biliary",

abstract = "Mg and its alloys have been tested in both bone and blood environment, but the degradation process in human bile have not been reported yet. In this case, commercial pure Mg and WE43 alloy were investigated in human bile to see the corrosion performance as potential biliary stent materials. The results revealed the weight loss of WE43 after 60 days immersion was only 1.87%. Moreover, WE43 performed a superior corrosion resistance to pure Mg, owing to more formation of the secondary reaction product Mg(H2PO4)2. The formation of H2PO4- instead of PO43- may be due to the fact that the compositions in the bile can prevent the formation of PO43- as it is the main composition of gallstone. The much slower corrosion rate of the WE43 alloy in human bile indicated that it may be good candidates as biliary stent materials.",

keywords = "Corrosion, Human bile, Key words Biomedical magnesium alloy, WE43",

author = "Yang Liu and Shengmin Zheng and Nan Li and Huahu Guo and Yufeng Zheng and Jirun Peng",

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T1 - Study on the in vitro degradation behavior of pure Mg and WE43 in human bile for 60 days for future usage in biliary

AU - Liu, Yang

AU - Zheng, Shengmin

AU - Li, Nan

AU - Guo, Huahu

AU - Zheng, Yufeng

AU - Peng, Jirun

PY - 2016/9/15

Y1 - 2016/9/15

N2 - Mg and its alloys have been tested in both bone and blood environment, but the degradation process in human bile have not been reported yet. In this case, commercial pure Mg and WE43 alloy were investigated in human bile to see the corrosion performance as potential biliary stent materials. The results revealed the weight loss of WE43 after 60 days immersion was only 1.87%. Moreover, WE43 performed a superior corrosion resistance to pure Mg, owing to more formation of the secondary reaction product Mg(H2PO4)2. The formation of H2PO4- instead of PO43- may be due to the fact that the compositions in the bile can prevent the formation of PO43- as it is the main composition of gallstone. The much slower corrosion rate of the WE43 alloy in human bile indicated that it may be good candidates as biliary stent materials.

AB - Mg and its alloys have been tested in both bone and blood environment, but the degradation process in human bile have not been reported yet. In this case, commercial pure Mg and WE43 alloy were investigated in human bile to see the corrosion performance as potential biliary stent materials. The results revealed the weight loss of WE43 after 60 days immersion was only 1.87%. Moreover, WE43 performed a superior corrosion resistance to pure Mg, owing to more formation of the secondary reaction product Mg(H2PO4)2. The formation of H2PO4- instead of PO43- may be due to the fact that the compositions in the bile can prevent the formation of PO43- as it is the main composition of gallstone. The much slower corrosion rate of the WE43 alloy in human bile indicated that it may be good candidates as biliary stent materials.

KW - Corrosion

KW - Human bile

KW - Key words Biomedical magnesium alloy

KW - WE43

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Study on the in vitro degradation behavior of pure Mg and WE43 in human bile for 60 days for future usage in biliary

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Keywords

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