RTNet: Relation Transformer Network for Diabetic Retinopathy Multi-Lesion Segmentation

Shiqi Huang, Jianan Li*, Yuze Xiao, Ning Shen, Tingfa Xu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

137 Citations (Scopus)
Plum Print visual indicator of research metrics
  • Citations
    • Citation Indexes: 135
  • Captures
    • Readers: 81
see details

Abstract

Automatic diabetic retinopathy (DR) lesions segmentation makes great sense of assisting ophthalmologists in diagnosis. Although many researches have been conducted on this task, most prior works paid too much attention to the designs of networks instead of considering the pathological association for lesions. Through investigating the pathogenic causes of DR lesions in advance, we found that certain lesions are closed to specific vessels and present relative patterns to each other. Motivated by the observation, we propose a relation transformer block (RTB) to incorporate attention mechanisms at two main levels: A self-Attention transformer exploits global dependencies among lesion features, while a cross-Attention transformer allows interactions between lesion and vessel features by integrating valuable vascular information to alleviate ambiguity in lesion detection caused by complex fundus structures. In addition, to capture the small lesion patterns first, we propose a global transformer block (GTB) which preserves detailed information in deep network. By integrating the above blocks of dual-branches, our network segments the four kinds of lesions simultaneously. Comprehensive experiments on IDRiD and DDR datasets well demonstrate the superiority of our approach, which achieves competitive performance compared to state-of-The-Arts.

Original languageEnglish
Pages (from-to)1596-1607
Number of pages12
JournalIEEE Transactions on Medical Imaging
Volume41
Issue number6
DOIs
Publication statusPublished - 1 Jun 2022

Keywords

  • Diabetic retinopathy
  • deep learning
  • fundus image
  • semantic segmentation
  • transformer

Fingerprint

Dive into the research topics of 'RTNet: Relation Transformer Network for Diabetic Retinopathy Multi-Lesion Segmentation'. Together they form a unique fingerprint.

Cite this

Huang, S., Li, J., Xiao, Y., Shen, N., & Xu, T. (2022). RTNet: Relation Transformer Network for Diabetic Retinopathy Multi-Lesion Segmentation. IEEE Transactions on Medical Imaging, 41(6), 1596-1607. https://doi.org/10.1109/TMI.2022.3143833