TY - JOUR
T1 - Reward prediction error in learning-related behaviors
AU - Deng, Yujun
AU - Song, Da
AU - Ni, Junjun
AU - Qing, Hong
AU - Quan, Zhenzhen
N1 - Publisher Copyright:
Copyright © 2023 Deng, Song, Ni, Qing and Quan.
PY - 2023
Y1 - 2023
N2 - Learning is a complex process, during which our opinions and decisions are easily changed due to unexpected information. But the neural mechanism underlying revision and correction during the learning process remains unclear. For decades, prediction error has been regarded as the core of changes to perception in learning, even driving the learning progress. In this article, we reviewed the concept of reward prediction error, and the encoding mechanism of dopaminergic neurons and the related neural circuities. We also discussed the relationship between reward prediction error and learning-related behaviors, including reversal learning. We then demonstrated the evidence of reward prediction error signals in several neurological diseases, including Parkinson’s disease and addiction. These observations may help to better understand the regulatory mechanism of reward prediction error in learning-related behaviors.
AB - Learning is a complex process, during which our opinions and decisions are easily changed due to unexpected information. But the neural mechanism underlying revision and correction during the learning process remains unclear. For decades, prediction error has been regarded as the core of changes to perception in learning, even driving the learning progress. In this article, we reviewed the concept of reward prediction error, and the encoding mechanism of dopaminergic neurons and the related neural circuities. We also discussed the relationship between reward prediction error and learning-related behaviors, including reversal learning. We then demonstrated the evidence of reward prediction error signals in several neurological diseases, including Parkinson’s disease and addiction. These observations may help to better understand the regulatory mechanism of reward prediction error in learning-related behaviors.
KW - associative learning
KW - dopamine
KW - reinforcement learning
KW - reversal learning
KW - reward prediction error
UR - http://www.scopus.com/inward/record.url?scp=85169571818&partnerID=8YFLogxK
U2 - 10.3389/fnins.2023.1171612
DO - 10.3389/fnins.2023.1171612
M3 - Review article
AN - SCOPUS:85169571818
SN - 1662-4548
VL - 17
JO - Frontiers in Neuroscience
JF - Frontiers in Neuroscience
M1 - 1171612
ER -