Research on the rough and precise correction method to the rotation axis position for optical projection image systems

Ma Ling, Wang Jihui*, Tan Qingwen, Li Gang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Since it was first presented in 2002, the Optical Projection Tomography(OPT) imaging system has emerged as a powerful tool for the study of a biomedical specimen on the mm to cm scale. In this paper, we present a rough and precise algorithm to further improve OPT image acquisition and tomographic reconstruction. The rough and precise algorithm combines the merits of the binarization process and the maximum correlation coefficient, and can accurately correct the displacement of the rotation axis. The tomographic images corrected by the rough and precise algorithm have higher image quality in the simulation experiments and specimen experiments. The reconstructed 3D images based on tomographic images can restore the original specimens. Thereby, the rough and precise algorithm contributes to increasing acquisition speed and quality of OPT data. More work should be performed to better understand and amend the rough and precise algorithm by abundant specimen experiments.

Original languageEnglish
Title of host publicationAdvanced Optical Imaging Technologies III
EditorsXiao-Cong Yuan, P. Scott Carney, Kebin Shi
PublisherSPIE
ISBN (Electronic)9781510639133
DOIs
Publication statusPublished - 2020
EventAdvanced Optical Imaging Technologies III 2020 - Virtual, Online, China
Duration: 11 Oct 202016 Oct 2020

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume11549
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceAdvanced Optical Imaging Technologies III 2020
Country/TerritoryChina
CityVirtual, Online
Period11/10/2016/10/20

Keywords

  • Artifact
  • Correction
  • Keyword:optical projection tomography
  • Projection data
  • Rotation axis

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