Abstract
The reduction of 4-nitrophenol catalyzed by nitroreductase in the presence of NADH was investigated in this paper. 4-Amino-phenol and 4-hydroxylamino-phenol were found in the reductive products. The relationship between reaction time and the reductive ratio were studied. The similar reducing ratios of 4-nitrophenol were obtained under aerobic and anaerobic conditions. The results indicated that an oxygen-insensitive reaction was proceeded in the reduction of 4-nitrophenol and nitroreductase was an oxygen-insensitive enzyme. The reductive products of 4-nitrophenol were determined by HPLC and MS.
| Original language | English |
|---|---|
| Pages (from-to) | 10-12 |
| Number of pages | 3 |
| Journal | Chinese Chemical Letters |
| Volume | 18 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 2007 |
Keywords
- 4-Nitrophenol
- Biotransformation
- Nitroreductase
- Reduction
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Chen, J., Dai, R. J., Tong, B., Xiao, S. Y., & Meng, W. (2007). Reduction of 4-nitrophenol catalyzed by nitroreductase. Chinese Chemical Letters, 18(1), 10-12. https://doi.org/10.1016/j.cclet.2006.11.009