Red blood cell partitioning and blood flux redistribution in microvascular bifurcation

Yuanqing Xu, Fangbao Tian*, Hanjun Li, Yulin Deng

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)

Abstract

This paper studies red blood cell (RBC) partitioning and blood flux redistribution in microvascular bifurcation by immersed boundary and lattice Boltzmann method. The effects of the initial position of RBC at low Reynolds number regime on the RBC deformation, RBC partitioning, blood flux redistribution and pressure distribution are discussed in detail. It is shown that the blood flux in the daughter branches and the initial position of RBC are important for RBC partitioning. RBC tends to enter the higher-flux-rate branch if the initial position of RBC is near the center of the mother vessel. The RBC may enter the lower-flux-rate branch if it is located near the wall of mother vessel on the lower-flux-rate branch side. Moreover, the blood flux is redistributed when an RBC presents in the daughter branch. Such redistribution is caused by the pressure distribution and reduces the superiority of RBC entering the same branch. The results obtained in the present work may provide a physical insight into the understanding of RBC partitioning and blood flux redistribution in microvascular bifurcation.

Original languageEnglish
Pages (from-to)24001
Number of pages1
JournalTheoretical and Applied Mechanics Letters
Volume2
Issue number2
DOIs
Publication statusPublished - 2012

Keywords

  • immersed boundary
  • lattice Boltzmann method
  • microvascular bifurcation
  • red blood cell

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