Abstract
Reaction of various carbonyl compounds with xenon difluoride in the presence of silicon tetrafluoride was investigated. Aromatic aldehyde, ketones, and α-ketoester react with xenon difluoride to give α,α-difluoroalkyl phenyl ethers. However, acid fluoride, ester, acid cyanide, α-ketocarboxylic acid, or thioester do not afford the corresponding products. In the case of cinnamaldehyde, fluorination was accompanied by intramolecular cyclization to afford fluorinated epoxide.
Original language | English |
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Pages (from-to) | 705-709 |
Number of pages | 5 |
Journal | Journal of Fluorine Chemistry |
Volume | 125 |
Issue number | 5 |
DOIs | |
Publication status | Published - May 2004 |
Externally published | Yes |
Keywords
- Carbonyl compound
- Cinnamaldehyde
- Cyclization
- Fluorination
- Rearrangement
- Silicon tetrafluoride
- Xenon difluoride