TY - GEN
T1 - Radical scavenging activity of various fractions of Cephalotaxus sinensis (Rehd et Wile) Li
AU - Saeed, Muhammad Khalid
AU - Deng, Yulin
AU - Parveen, Z.
AU - Dai, Rongji
AU - Ahmad, W.
AU - Yu, Hong
PY - 2007
Y1 - 2007
N2 - Cephalotaxus sinensis (Rend et Wile) Li, belongs to family Cephalotaxaceae, common in China, is an indigenous medicinal plant due to its antiascariasis, antiinflammation, anticough and antidyspepsia activity. The overindulgence of free radicals has been concerned in the development of chronic diseases and play an imperative role in the development of neurodegenerative disorders, such as Alzheimer's and Parkinson's diseases. Various fractions of this plant were evaluated for their radical scavenging activity by the DPPH· and reducing power activity assays. Also, the Folin-Ciocalteu method was used to determine the total phenolic content. The results of both methods revealed that Cephalotaxus. sinensis possesses potent antioxidant activity. The polyphenolic content and antioxidant activities of the different fractions tested decreased in the order of EaF > BtF > CfF > WtF > PtF. The radical scavenging activity of the ethyl acetate fraction higher than BHT and slightly lower than Vit-C. A positive linear correlation between antioxidant activity and contents of polyphenol was established. This information shows that ethyl acetate fraction of C. sinensis can be used as antioxidant in medicinal preparations.
AB - Cephalotaxus sinensis (Rend et Wile) Li, belongs to family Cephalotaxaceae, common in China, is an indigenous medicinal plant due to its antiascariasis, antiinflammation, anticough and antidyspepsia activity. The overindulgence of free radicals has been concerned in the development of chronic diseases and play an imperative role in the development of neurodegenerative disorders, such as Alzheimer's and Parkinson's diseases. Various fractions of this plant were evaluated for their radical scavenging activity by the DPPH· and reducing power activity assays. Also, the Folin-Ciocalteu method was used to determine the total phenolic content. The results of both methods revealed that Cephalotaxus. sinensis possesses potent antioxidant activity. The polyphenolic content and antioxidant activities of the different fractions tested decreased in the order of EaF > BtF > CfF > WtF > PtF. The radical scavenging activity of the ethyl acetate fraction higher than BHT and slightly lower than Vit-C. A positive linear correlation between antioxidant activity and contents of polyphenol was established. This information shows that ethyl acetate fraction of C. sinensis can be used as antioxidant in medicinal preparations.
KW - Cephalotaxus sinensis
KW - DPPH
KW - Extraction
KW - Fractionation
KW - Polyphenols
KW - Reducing power activity
UR - http://www.scopus.com/inward/record.url?scp=48149104522&partnerID=8YFLogxK
U2 - 10.1109/ICCME.2007.4382027
DO - 10.1109/ICCME.2007.4382027
M3 - Conference contribution
AN - SCOPUS:48149104522
SN - 1424410789
SN - 9781424410781
T3 - 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
SP - 1651
EP - 1654
BT - 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
T2 - 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
Y2 - 23 May 2007 through 27 May 2007
ER -