Preparation and characterization of 3-(triethoxysilyl) propyl isocyanate self-assembled monolayer on surface of chip

Yao Xie, Lina Geng, Feng Qu, Aiqin Luo, Yulin Deng*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Monolayer of 3-(triethoxysilyl) propyl isocyanate was prepared on the slide by self-assembled technique. X-ray photoelectron spectroscopy (XPS) was employed to analyze the elementary composition of the film. Contact angle of distilled water was measured to characterize the surface state. It was shown that 3-(triethoxysilyl) propyl isocyanate had been successfully assembled on the slide. The increase of contact angle to 80° demonstrated that the hydrophobicity of the surface of chip was increased significantly. Moreover, further self-assembly of bovine serum albumin (BSA) on 3-(triethoxysilyl) propyl isocyanate was also carried out with the advantages such as simple and convenient preparation. Therefore, the potential of broader applications in the modification of micro-channel in the μ-TAS system, the immobilization of protein or peptide and the surface modification of materials are all expectative.

Original languageEnglish
Pages (from-to)738-742
Number of pages5
JournalChinese Science Bulletin
Volume54
Issue number5
DOIs
Publication statusPublished - Mar 2009

Keywords

  • 3-(triethoxysilyl) propyl isocyanate
  • Characterization
  • Covalent bonding
  • Self-assembled monolayers

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