Preparation and application of sodium polyacrylate-chitosan interpenetrating polymer sponge

Sodium polyacrylate-chitosan interpenetrating polymer network was synthesized in acetic acid solution with sodium polyacrylate and chitosan as raw materials, glutaraldehyde as crosslinker. After freezing dry, the interpenetrating polymer sponge was prepared. The molecular structure of the sponge was confirmed by Fourier transform infrared spectrum(FT-IR), and the surface morphologies were examined by scanning electron microscope (SEM). The factors of influencing the swelling properties were studied. It is found that the optimum reaction condition for synthesizing the sponge with the relatively good swelling properties was that m_CTS:m_PAANa=1:1.11, m_{glutaraldehyde}:m_CTS=1:0.189. The pores superabsorbent sponge prepared through these conditions could absorb over 129 g/g distilled water. The model drug acetaminophen was added during the process of preparing the sponge. It is found that the model drug immolilized in the network structure can be slow released from the sponge.