Zhang, L., Wei, C., Wu, J., Liu, D., Yao, Y., Chen, Z., Liu, J., Yao, C. J., Li, D., Yang, R., & Xia, Z. (2022). Photoinduced inverse Sonogashira coupling reaction. Chemical Science, 13(25), 7475-7481. https://doi.org/10.1039/d2sc01933g
Zhang, Lizhu ; Wei, Cunbo ; Wu, Jiawen et al. / Photoinduced inverse Sonogashira coupling reaction. In: Chemical Science. 2022 ; Vol. 13, No. 25. pp. 7475-7481.
@article{44ed482870b44a969f92b9b003e38d3a,
title = "Photoinduced inverse Sonogashira coupling reaction",
abstract = "Alkynes are widely used in chemistry, medicine and materials science. Here we demonstrate a transition-metal and photocatalyst-free inverse Sonogashira coupling reaction between iodoalkynes and (hetero)arenes or alkenes under visible-light irradiation. Mechanistic and computational studies suggest that iodoalkynes can be directly activated by visible light irradiation, and an excited state iodoalkyne acted as an “alkynyl radical synthetic equivalent”, reacting with a series of C(sp2)-H bonds for coupling products. This work should open new windows in radical chemistry and alkynylation method.",
author = "Lizhu Zhang and Cunbo Wei and Jiawen Wu and Dan Liu and Yinchao Yao and Zhuo Chen and Jianxun Liu and Yao, {Chang Jiang} and Dinghua Li and Rongjie Yang and Zhonghua Xia",
note = "Publisher Copyright: {\textcopyright} 2022 The Royal Society of Chemistry.",
year = "2022",
month = may,
day = "30",
doi = "10.1039/d2sc01933g",
language = "English",
volume = "13",
pages = "7475--7481",
journal = "Chemical Science",
issn = "2041-6520",
publisher = "Royal Society of Chemistry",
number = "25",
}
Zhang, L, Wei, C, Wu, J, Liu, D, Yao, Y, Chen, Z, Liu, J, Yao, CJ, Li, D, Yang, R & Xia, Z 2022, 'Photoinduced inverse Sonogashira coupling reaction', Chemical Science, vol. 13, no. 25, pp. 7475-7481. https://doi.org/10.1039/d2sc01933g
Photoinduced inverse Sonogashira coupling reaction. / Zhang, Lizhu; Wei, Cunbo; Wu, Jiawen et al.
In:
Chemical Science, Vol. 13, No. 25, 30.05.2022, p. 7475-7481.
Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - Photoinduced inverse Sonogashira coupling reaction
AU - Zhang, Lizhu
AU - Wei, Cunbo
AU - Wu, Jiawen
AU - Liu, Dan
AU - Yao, Yinchao
AU - Chen, Zhuo
AU - Liu, Jianxun
AU - Yao, Chang Jiang
AU - Li, Dinghua
AU - Yang, Rongjie
AU - Xia, Zhonghua
N1 - Publisher Copyright:
© 2022 The Royal Society of Chemistry.
PY - 2022/5/30
Y1 - 2022/5/30
N2 - Alkynes are widely used in chemistry, medicine and materials science. Here we demonstrate a transition-metal and photocatalyst-free inverse Sonogashira coupling reaction between iodoalkynes and (hetero)arenes or alkenes under visible-light irradiation. Mechanistic and computational studies suggest that iodoalkynes can be directly activated by visible light irradiation, and an excited state iodoalkyne acted as an “alkynyl radical synthetic equivalent”, reacting with a series of C(sp2)-H bonds for coupling products. This work should open new windows in radical chemistry and alkynylation method.
AB - Alkynes are widely used in chemistry, medicine and materials science. Here we demonstrate a transition-metal and photocatalyst-free inverse Sonogashira coupling reaction between iodoalkynes and (hetero)arenes or alkenes under visible-light irradiation. Mechanistic and computational studies suggest that iodoalkynes can be directly activated by visible light irradiation, and an excited state iodoalkyne acted as an “alkynyl radical synthetic equivalent”, reacting with a series of C(sp2)-H bonds for coupling products. This work should open new windows in radical chemistry and alkynylation method.
UR - http://www.scopus.com/inward/record.url?scp=85131750576&partnerID=8YFLogxK
U2 - 10.1039/d2sc01933g
DO - 10.1039/d2sc01933g
M3 - Article
AN - SCOPUS:85131750576
SN - 2041-6520
VL - 13
SP - 7475
EP - 7481
JO - Chemical Science
JF - Chemical Science
IS - 25
ER -
Zhang L, Wei C, Wu J, Liu D, Yao Y, Chen Z et al. Photoinduced inverse Sonogashira coupling reaction. Chemical Science. 2022 May 30;13(25):7475-7481. doi: 10.1039/d2sc01933g