Abstract
A new domino reaction for Nazarov reagents: An efficient approach was developed for the construction of highly functionalized conjugated 2,3-dihydrofuran skeletons. Nazarov reagents were used for the first time in a phosphine-catalyzed domino reaction and successfully used to construct five-membered ring compounds using alcohol as the solvent. DFT calculations indicate that alcohol is essential for the catalysis of the [1,2]-proton transfer.
| Original language | English |
|---|---|
| Pages (from-to) | 1533-1537 |
| Number of pages | 5 |
| Journal | Chemistry - An Asian Journal |
| Volume | 7 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jun 2012 |
| Externally published | Yes |
Keywords
- Nazarov reagent
- allenoates
- dihydrofurans
- domino reactions
- phosphine
Fingerprint
Dive into the research topics of 'Phosphine-catalyzed domino reaction for the synthesis of conjugated 2,3-dihydrofurans from allenoates and Nazarov reagents'. Together they form a unique fingerprint.Cite this
Xie, P., Lai, W., Geng, Z., Huang, Y., & Chen, R. (2012). Phosphine-catalyzed domino reaction for the synthesis of conjugated 2,3-dihydrofurans from allenoates and Nazarov reagents. Chemistry - An Asian Journal, 7(7), 1533-1537. https://doi.org/10.1002/asia.201200140