Organic room-temperature phosphorescence materials for bioimaging

Yahui Zhang; Hairong Li; Mengdie Yang; Wenbo Dai; Jianbing Shi; Bin Tong; Zhengxu Cai; Zhouyu Wang; Yuping Dong; Xiaoqi Yu

doi:10.1039/d3cc00923h

Organic room-temperature phosphorescence materials for bioimaging

Yahui Zhang, Hairong Li, Mengdie Yang, Wenbo Dai, Jianbing Shi, Bin Tong, Zhengxu Cai^*, Zhouyu Wang^*, Yuping Dong, Xiaoqi Yu^*

^*Corresponding author for this work

School of Material Science and Engineering

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

Organic room-temperature phosphorescence (RTP) materials are currently the focus of research in the field of bioimaging. In comparison with the conventional imaging modalities based on organic fluorescent dyes, RTP materials with long lifetime enable time-resolved imaging to improve the imaging resolution by avoiding autofluorescence. In this review, we will start with summarizing strategies for achieving high performance RTP materials for bioimaging, including the development of RTP-compounds, host-guest doping materials, and supramolecular assemblies. We then discuss the optimization of nanonization processes to obtain RTP nanoparticles with controllable size, high dispersibility, and improved stability. The differences between top-down and bottom-up approaches are further described. Finally, we briefly introduce the emerging methods for preparing RTP materials for bioimaging.

Original language	English
Pages (from-to)	5329-5342
Number of pages	14
Journal	Chemical Communications
Volume	59
Issue number	36
DOIs	https://doi.org/10.1039/d3cc00923h
Publication status	Published - 3 Apr 2023

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title = "Organic room-temperature phosphorescence materials for bioimaging",

abstract = "Organic room-temperature phosphorescence (RTP) materials are currently the focus of research in the field of bioimaging. In comparison with the conventional imaging modalities based on organic fluorescent dyes, RTP materials with long lifetime enable time-resolved imaging to improve the imaging resolution by avoiding autofluorescence. In this review, we will start with summarizing strategies for achieving high performance RTP materials for bioimaging, including the development of RTP-compounds, host-guest doping materials, and supramolecular assemblies. We then discuss the optimization of nanonization processes to obtain RTP nanoparticles with controllable size, high dispersibility, and improved stability. The differences between top-down and bottom-up approaches are further described. Finally, we briefly introduce the emerging methods for preparing RTP materials for bioimaging.",

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T1 - Organic room-temperature phosphorescence materials for bioimaging

AU - Zhang, Yahui

AU - Li, Hairong

AU - Yang, Mengdie

AU - Dai, Wenbo

AU - Shi, Jianbing

AU - Tong, Bin

AU - Cai, Zhengxu

AU - Wang, Zhouyu

AU - Dong, Yuping

AU - Yu, Xiaoqi

PY - 2023/4/3

Y1 - 2023/4/3

N2 - Organic room-temperature phosphorescence (RTP) materials are currently the focus of research in the field of bioimaging. In comparison with the conventional imaging modalities based on organic fluorescent dyes, RTP materials with long lifetime enable time-resolved imaging to improve the imaging resolution by avoiding autofluorescence. In this review, we will start with summarizing strategies for achieving high performance RTP materials for bioimaging, including the development of RTP-compounds, host-guest doping materials, and supramolecular assemblies. We then discuss the optimization of nanonization processes to obtain RTP nanoparticles with controllable size, high dispersibility, and improved stability. The differences between top-down and bottom-up approaches are further described. Finally, we briefly introduce the emerging methods for preparing RTP materials for bioimaging.

AB - Organic room-temperature phosphorescence (RTP) materials are currently the focus of research in the field of bioimaging. In comparison with the conventional imaging modalities based on organic fluorescent dyes, RTP materials with long lifetime enable time-resolved imaging to improve the imaging resolution by avoiding autofluorescence. In this review, we will start with summarizing strategies for achieving high performance RTP materials for bioimaging, including the development of RTP-compounds, host-guest doping materials, and supramolecular assemblies. We then discuss the optimization of nanonization processes to obtain RTP nanoparticles with controllable size, high dispersibility, and improved stability. The differences between top-down and bottom-up approaches are further described. Finally, we briefly introduce the emerging methods for preparing RTP materials for bioimaging.

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Organic room-temperature phosphorescence materials for bioimaging

Abstract

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