Optical coherence tomography microvascular imaging method based on svOCT and cmOCT

Juan Wang, Liquan Dong*, Lingqin Kong, Ming Liu, Mei Hui, Yuejin Zhao

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

OCT is a new imaging technology based on the principle of Michelson interferometer to perform tomography of sample tissue. OCT has the characteristics of high-resolution, non-invasive, real-time detection, and non-destructive imaging. The OCT vascular imaging method can generate high-contrast microvascular images without injecting a contrast agent. This paper presents a new microvascular imaging method (sv-cmOCT) that combines two existing microvascular imaging methods - speckle variance optical coherence tomography (svOCT) and correlation mapping optical coherence tomography (cmOCT). The binarised image of svOCT is used to mask the cmOCT image, which can effectively suppress background noise and static artefacts, and ultimately generate a microvascular image with high contrast. In this paper, blood flow mimic experiments and animal experiments were designed to validate the imaging performance of the microvascular imaging method. It is demonstrated that the proposed method can improve the signal-to-noise ratio of microvascular images well compared to methods such as svOCT and cmOCT and B-scan mask cmOCT.

Original languageEnglish
Title of host publication2021 International Conference on Optical Instruments and Technology
Subtitle of host publicationOptical Systems, Optoelectronic Instruments, Novel Display, and Imaging Technology
EditorsJuan Liu, Baohua Jia, Liangcai Cao, Xincheng Yao, Yongtian Wang, Takanori Nomura
PublisherSPIE
ISBN (Electronic)9781510655591
DOIs
Publication statusPublished - 2022
Event2021 International Conference on Optical Instruments and Technology: Optical Systems, Optoelectronic Instruments, Novel Display, and Imaging Technology - Virtual, Online, China
Duration: 8 Apr 202210 Apr 2022

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume12277
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

Conference2021 International Conference on Optical Instruments and Technology: Optical Systems, Optoelectronic Instruments, Novel Display, and Imaging Technology
Country/TerritoryChina
CityVirtual, Online
Period8/04/2210/04/22

Keywords

  • cmOCT
  • microvascular imaging
  • optical coherence tomography
  • svOCT

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