Abstract
A new main-chain polyrotaxanes was prepared through the ATRP (atom transfer radical polymerization) of HPMA (2-hydroxypropyl methacrylate) initiated with poly-pseudorotaxanes made fromα or β-CD self-assembly with a distal 2-bromoisobutyryl end-capped Pluronic F127 in the presence of Cu(I)Br/PMDETA at 25°C in aqueous media. All the GPC traces exhibited a narrow molecular weight distribution with a polydispersity index of 1.26-1.42 for α-CD and 1.41-1.84 for β-CD derived PR. The x-ray diffraction confirmed that both the α or β-CD containing PRs adopt crystalline inclusion complexes featured with the channel type structure and α-CD selectively include PEG blocks. The DSC analysis revealed that β-CD are dispersed on the Pluronic F127 chain without selectivity. The ATRP offers the opportunity to prepare polyrotaxanes with adjustable end stoppers as smart materials for supramolecular sliding gels, biosensors, controlled drug release, etc.
| Original language | English |
|---|---|
| Pages (from-to) | 5283-5293 |
| Number of pages | 11 |
| Journal | Journal of Polymer Science, Part A: Polymer Chemistry |
| Volume | 46 |
| Issue number | 15 |
| DOIs | |
| Publication status | Published - 1 Aug 2008 |
Keywords
- ATRP
- Block copolymers
- Cyclodextrin
- HPMA
- Pluronic F127 polyrotaxane