Near-infrared Mueller matrix imaging for colonic cancer detection

Jianfeng Wang, Wei Zheng, Kan Lin, Zhiwei Huang*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Mueller matrix imaging along with polar decomposition method was employed for the colonic cancer detection by polarized light in the near-infrared spectral range (700-1100 nm). A high-speed (<5s) Muller matrix imaging system with dual-rotating waveplates was developed. 16 (4 by 4) full Mueller matrices of the colonic tissues (i.e., normal and caner) were acquired. Polar decomposition was further implemented on the 16 images to derive the diattentuation, depolarization, and the retardance images. The decomposed images showed clear margin between the normal and cancerous colon tissue samples. The work shows the potential of near-infrared Mueller matrix imaging for the early diagnosis and detection of malignant lesions in the colon.

Original languageEnglish
Title of host publicationOptical Biopsy XIV
Subtitle of host publicationToward Real-Time Spectroscopic Imaging and Diagnosis
EditorsRobert R. Alfano, Stavros G. Demos
PublisherSPIE
ISBN (Electronic)9781628419375
DOIs
Publication statusPublished - 2016
Externally publishedYes
EventOptical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis - San Francisco, United States
Duration: 15 Feb 201617 Feb 2016

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9703
ISSN (Print)1605-7422

Conference

ConferenceOptical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis
Country/TerritoryUnited States
CitySan Francisco
Period15/02/1617/02/16

Keywords

  • Colonic Cancer
  • Mueller Matrix Imaging

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