Li, Z., Wang, B., Luo, W., Xu, Y., Wang, J., Xue, Z., Niu, Y., Cheng, Z., Ge, S., Zhang, W., Zhang, J., Li, Q., & Chong, K. (2023). Natural variation of codon repeats in COLD11 endows rice with chilling resilience. Science advances, 9(1), Article eabq5506. https://doi.org/10.1126/sciadv.abq5506
Li, Zhitao ; Wang, Bo ; Luo, Wei et al. / Natural variation of codon repeats in COLD11 endows rice with chilling resilience. In: Science advances. 2023 ; Vol. 9, No. 1.
@article{2c74b3d59a414e88b5d5a3ffbb5dbb43,
title = "Natural variation of codon repeats in COLD11 endows rice with chilling resilience",
abstract = "Abnormal temperature caused by global climate change threatens the rice production. Defense signaling network for chilling has been uncovered in plants. However, less is known about repairing DNA damage produced from overwhelmed defense and its evolution during domestication. Here, we genetically identified a major QTL, COLD11, using the data-merging genome-wide association study based on an algorithm combining polarized data from two subspecies, indica and japonica, into one system. Rice loss-of-function mutations of COLD11 caused reduced chilling tolerance. Genome evolution analysis of representative rice germplasms suggested that numbers of GCG sequence repeats in the first exon of COLD11 were subjected to strong domestication selection during the northern expansion of rice planting. The repeat numbers affected the biochemical activity of DNA repair protein COLD11/RAD51A1 in renovating DNA damage under chilling stress. Our findings highlight a potential way to finely manipulate key genes in rice genome and effectively improve chilling tolerance through molecular designing.",
author = "Zhitao Li and Bo Wang and Wei Luo and Yunyuan Xu and Jinjuan Wang and Zhihui Xue and Yuda Niu and Zhukuan Cheng and Song Ge and Wei Zhang and Jingyu Zhang and Qizhai Li and Kang Chong",
note = "Publisher Copyright: Copyright {\textcopyright} 2023 The Authors, some rights reserved.",
year = "2023",
month = jan,
doi = "10.1126/sciadv.abq5506",
language = "English",
volume = "9",
journal = "Science advances",
issn = "2375-2548",
publisher = "American Association for the Advancement of Science",
number = "1",
}
Li, Z, Wang, B, Luo, W, Xu, Y, Wang, J, Xue, Z, Niu, Y, Cheng, Z, Ge, S, Zhang, W, Zhang, J, Li, Q & Chong, K 2023, 'Natural variation of codon repeats in COLD11 endows rice with chilling resilience', Science advances, vol. 9, no. 1, eabq5506. https://doi.org/10.1126/sciadv.abq5506
Natural variation of codon repeats in COLD11 endows rice with chilling resilience. / Li, Zhitao; Wang, Bo; Luo, Wei et al.
In:
Science advances, Vol. 9, No. 1, eabq5506, 01.2023.
Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - Natural variation of codon repeats in COLD11 endows rice with chilling resilience
AU - Li, Zhitao
AU - Wang, Bo
AU - Luo, Wei
AU - Xu, Yunyuan
AU - Wang, Jinjuan
AU - Xue, Zhihui
AU - Niu, Yuda
AU - Cheng, Zhukuan
AU - Ge, Song
AU - Zhang, Wei
AU - Zhang, Jingyu
AU - Li, Qizhai
AU - Chong, Kang
N1 - Publisher Copyright:
Copyright © 2023 The Authors, some rights reserved.
PY - 2023/1
Y1 - 2023/1
N2 - Abnormal temperature caused by global climate change threatens the rice production. Defense signaling network for chilling has been uncovered in plants. However, less is known about repairing DNA damage produced from overwhelmed defense and its evolution during domestication. Here, we genetically identified a major QTL, COLD11, using the data-merging genome-wide association study based on an algorithm combining polarized data from two subspecies, indica and japonica, into one system. Rice loss-of-function mutations of COLD11 caused reduced chilling tolerance. Genome evolution analysis of representative rice germplasms suggested that numbers of GCG sequence repeats in the first exon of COLD11 were subjected to strong domestication selection during the northern expansion of rice planting. The repeat numbers affected the biochemical activity of DNA repair protein COLD11/RAD51A1 in renovating DNA damage under chilling stress. Our findings highlight a potential way to finely manipulate key genes in rice genome and effectively improve chilling tolerance through molecular designing.
AB - Abnormal temperature caused by global climate change threatens the rice production. Defense signaling network for chilling has been uncovered in plants. However, less is known about repairing DNA damage produced from overwhelmed defense and its evolution during domestication. Here, we genetically identified a major QTL, COLD11, using the data-merging genome-wide association study based on an algorithm combining polarized data from two subspecies, indica and japonica, into one system. Rice loss-of-function mutations of COLD11 caused reduced chilling tolerance. Genome evolution analysis of representative rice germplasms suggested that numbers of GCG sequence repeats in the first exon of COLD11 were subjected to strong domestication selection during the northern expansion of rice planting. The repeat numbers affected the biochemical activity of DNA repair protein COLD11/RAD51A1 in renovating DNA damage under chilling stress. Our findings highlight a potential way to finely manipulate key genes in rice genome and effectively improve chilling tolerance through molecular designing.
UR - http://www.scopus.com/inward/record.url?scp=85145870257&partnerID=8YFLogxK
U2 - 10.1126/sciadv.abq5506
DO - 10.1126/sciadv.abq5506
M3 - Article
C2 - 36608134
AN - SCOPUS:85145870257
SN - 2375-2548
VL - 9
JO - Science advances
JF - Science advances
IS - 1
M1 - eabq5506
ER -
Li Z, Wang B, Luo W, Xu Y, Wang J, Xue Z et al. Natural variation of codon repeats in COLD11 endows rice with chilling resilience. Science advances. 2023 Jan;9(1):eabq5506. doi: 10.1126/sciadv.abq5506
