Natural hydrogels applied in photodynamic therapy

Zhipan Feng; Shiying Lin; Andrew McDonagh; Chen Yu

doi:10.2174/0929867326666191016112828

Natural hydrogels applied in photodynamic therapy

Zhipan Feng, Shiying Lin, Andrew McDonagh^*, Chen Yu

^*Corresponding author for this work

School of Material Science and Engineering

Research output: Contribution to journal › Review article › peer-review

8 Citations (Scopus)

Abstract

Natural hydrogels are three-dimensional (3D) water-retaining materials with a skeleton consisting of natural polymers, their derivatives or mixtures. Natural hydrogels can provide sustained or controlled drug release and possess some unique properties of natural polymers, such as biodegradabil-ity, biocompatibility and some additional functions, such as CD44 targeting of hyaluronic acid. Natural hydrogels can be used with photosensitizers (PSs) in photodynamic therapy (PDT) to increase the range of applications. In the current review, the pertinent design variables are discussed along with a descrip-tion of the categories of natural hydrogels available for PDT.

Original language	English
Pages (from-to)	2681-2703
Number of pages	23
Journal	Current Medicinal Chemistry
Volume	27
Issue number	16
DOIs	https://doi.org/10.2174/0929867326666191016112828
Publication status	Published - 2020

Keywords

Hydrogel
Natural polymer
PDT
Photodynamic therapy
ROS
Reactive oxygen species

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10.2174/0929867326666191016112828

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title = "Natural hydrogels applied in photodynamic therapy",

abstract = "Natural hydrogels are three-dimensional (3D) water-retaining materials with a skeleton consisting of natural polymers, their derivatives or mixtures. Natural hydrogels can provide sustained or controlled drug release and possess some unique properties of natural polymers, such as biodegradabil-ity, biocompatibility and some additional functions, such as CD44 targeting of hyaluronic acid. Natural hydrogels can be used with photosensitizers (PSs) in photodynamic therapy (PDT) to increase the range of applications. In the current review, the pertinent design variables are discussed along with a descrip-tion of the categories of natural hydrogels available for PDT.",

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AU - Feng, Zhipan

AU - Lin, Shiying

AU - McDonagh, Andrew

AU - Yu, Chen

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AB - Natural hydrogels are three-dimensional (3D) water-retaining materials with a skeleton consisting of natural polymers, their derivatives or mixtures. Natural hydrogels can provide sustained or controlled drug release and possess some unique properties of natural polymers, such as biodegradabil-ity, biocompatibility and some additional functions, such as CD44 targeting of hyaluronic acid. Natural hydrogels can be used with photosensitizers (PSs) in photodynamic therapy (PDT) to increase the range of applications. In the current review, the pertinent design variables are discussed along with a descrip-tion of the categories of natural hydrogels available for PDT.

KW - Hydrogel

KW - Natural polymer

KW - PDT

KW - Photodynamic therapy

KW - ROS

KW - Reactive oxygen species

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JO - Current Medicinal Chemistry

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Natural hydrogels applied in photodynamic therapy

Abstract

Keywords

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