Abstract
A clean green, efficient and facile protocol was developed for the synthesis of a series of 2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones in water with good yield by the reaction of 2-amino-nicotinonitriles with carbonyls catalyzed by DBU under microwave irradiation. The DBU–H2O system can be recycled five times without activity loss.
Original language | English |
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Pages (from-to) | 945-951 |
Number of pages | 7 |
Journal | Green Chemistry |
Volume | 14 |
Issue number | 4 |
DOIs | |
Publication status | Published - Apr 2012 |