TY - JOUR
T1 - Liver tumor segmentation in CT volumes using an adversarial densely connected network
AU - Chen, Lei
AU - Song, Hong
AU - Wang, Chi
AU - Cui, Yutao
AU - Yang, Jian
AU - Hu, Xiaohua
AU - Zhang, Le
N1 - Publisher Copyright:
© 2019 The Author(s).
PY - 2019/12/2
Y1 - 2019/12/2
N2 - Background: Malignant liver tumor is one of the main causes of human death. In order to help physician better diagnose and make personalized treatment schemes, in clinical practice, it is often necessary to segment and visualize the liver tumor from abdominal computed tomography images. Due to the large number of slices in computed tomography sequence, developing an automatic and reliable segmentation method is very favored by physicians. However, because of the noise existed in the scan sequence and the similar pixel intensity of liver tumors with their surrounding tissues, besides, the size, position and shape of tumors also vary from one patient to another, automatic liver tumor segmentation is still a difficult task. Results: We perform the proposed algorithm to the Liver Tumor Segmentation Challenge dataset and evaluate the segmentation results. Experimental results reveal that the proposed method achieved an average Dice score of 68.4% for tumor segmentation by using the designed network, and ASD, MSD, VOE and RVD improved from 27.8 to 21, 147 to 124, 0.52 to 0.46 and 0.69 to 0.73, respectively after performing adversarial training strategy, which proved the effectiveness of the proposed method. Conclusions: The testing results show that the proposed method achieves improved performance, which corroborated the adversarial training based strategy can achieve more accurate and robustness results on liver tumor segmentation task.
AB - Background: Malignant liver tumor is one of the main causes of human death. In order to help physician better diagnose and make personalized treatment schemes, in clinical practice, it is often necessary to segment and visualize the liver tumor from abdominal computed tomography images. Due to the large number of slices in computed tomography sequence, developing an automatic and reliable segmentation method is very favored by physicians. However, because of the noise existed in the scan sequence and the similar pixel intensity of liver tumors with their surrounding tissues, besides, the size, position and shape of tumors also vary from one patient to another, automatic liver tumor segmentation is still a difficult task. Results: We perform the proposed algorithm to the Liver Tumor Segmentation Challenge dataset and evaluate the segmentation results. Experimental results reveal that the proposed method achieved an average Dice score of 68.4% for tumor segmentation by using the designed network, and ASD, MSD, VOE and RVD improved from 27.8 to 21, 147 to 124, 0.52 to 0.46 and 0.69 to 0.73, respectively after performing adversarial training strategy, which proved the effectiveness of the proposed method. Conclusions: The testing results show that the proposed method achieves improved performance, which corroborated the adversarial training based strategy can achieve more accurate and robustness results on liver tumor segmentation task.
KW - CT
KW - Fully convolutional neural network
KW - Liver segmentation
KW - Liver tumor segmentation
UR - http://www.scopus.com/inward/record.url?scp=85075872997&partnerID=8YFLogxK
U2 - 10.1186/s12859-019-3069-x
DO - 10.1186/s12859-019-3069-x
M3 - Article
C2 - 31787071
AN - SCOPUS:85075872997
SN - 1471-2105
VL - 20
JO - BMC Bioinformatics
JF - BMC Bioinformatics
M1 - 587
ER -