TY - JOUR
T1 - Large time behavior of solution to a fully parabolic chemotaxis-haptotaxis model in higher dimensions
AU - Wang, Yifu
AU - Ke, Yuanyuan
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/5/5
Y1 - 2016/5/5
N2 - This paper deals with the chemotaxis-haptotaxis model of cancer invasion in a bounded smooth domain Ω⊂Rn with zero-flux boundary conditions, where χ, ξ and μ are positive parameters. It is shown that if μ/χ is suitably large then for all sufficiently smooth initial data, the associated initial-boundary-value problem possesses a unique global-in-time classical solution that is bounded in Ω×(0, ∞), and if the initial data w0 is small, w becomes asymptotically negligible. Moreover, we prove that when domain Ω is convex, (1μ,1μ,0) is globally asymptotically stable provided that u0≢0 and thereby extends the result of Hillen et al. (2013) [18] to the higher space dimensions.
AB - This paper deals with the chemotaxis-haptotaxis model of cancer invasion in a bounded smooth domain Ω⊂Rn with zero-flux boundary conditions, where χ, ξ and μ are positive parameters. It is shown that if μ/χ is suitably large then for all sufficiently smooth initial data, the associated initial-boundary-value problem possesses a unique global-in-time classical solution that is bounded in Ω×(0, ∞), and if the initial data w0 is small, w becomes asymptotically negligible. Moreover, we prove that when domain Ω is convex, (1μ,1μ,0) is globally asymptotically stable provided that u0≢0 and thereby extends the result of Hillen et al. (2013) [18] to the higher space dimensions.
KW - Asymptotic stability
KW - Cancer invasion
KW - Chemotaxis
KW - Haptotaxis
UR - http://www.scopus.com/inward/record.url?scp=84958111225&partnerID=8YFLogxK
U2 - 10.1016/j.jde.2016.01.017
DO - 10.1016/j.jde.2016.01.017
M3 - Article
AN - SCOPUS:84958111225
SN - 0022-0396
VL - 260
SP - 6960
EP - 6988
JO - Journal of Differential Equations
JF - Journal of Differential Equations
IS - 9
ER -