Iodine catalyzed three-component Strecker-type synthesis of α-aminonitriles from aldehydes, amines and tributyltin cyanide

Hong She Wang*, Li Fang Zhao, Zhi Ming Du

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

A simple and efficient one-pot method has been developed for the synthesis of α-aminonitriles from aldehydes, amines and tributyltin cyanide in the presence of a catalytic amount of iodine with high yields. The reactions proceeded smoothly at room temperature via very simple procedure.

Original languageEnglish
Pages (from-to)135-137
Number of pages3
JournalChinese Journal of Chemistry
Volume24
Issue number1
DOIs
Publication statusPublished - Jan 2006

Keywords

  • Iodine
  • Strecker reaction
  • Tributyltin cyanide
  • α-aminonitrile

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