TY - JOUR
T1 - Hematoma volume measurement in gradient echo MRI using quantitative susceptibility mapping
AU - Wang, Shuo
AU - Lou, Min
AU - Liu, Tian
AU - Cui, Deqi
AU - Chen, Xiaomei
AU - Wang, Yi
PY - 2013/8
Y1 - 2013/8
N2 - BACKGROUND AND PURPOSE-: A novel quantitative susceptibility mapping (QSM) processing technology has been developed to map tissue susceptibility property without blooming artifacts. We hypothesize that hematoma volume measurement on QSM is independent of imaging parameters, eliminating its echo time dependence on gradient echo MRI. METHODS-: Gradient echo MRI of 16 patients with intracerebral hemorrhage was processed with susceptibility-weighted imaging, R* (=1/T2*) mapping, and QSM at various echo times. Hematoma volumes were measured from these images. RESULTS-: Linear regression of hematoma volume versus echo time showed substantial slopes for gradient echo magnitude (0.45±0.31 L/s), susceptibility-weighted imaging (0.52±0.46), and R* (0.39±0.30) but nearly zero slope for QSM (0.01±0.05). At echo time=20 ms, hematoma volume on QSM was 0.80× that on gradient echo magnitude image (R2=0.99). CONCLUSIONS-: QSM can provide reliable measurement of hematoma volume, which can be performed rapidly and accurately using a semiautomated segmentation tool.
AB - BACKGROUND AND PURPOSE-: A novel quantitative susceptibility mapping (QSM) processing technology has been developed to map tissue susceptibility property without blooming artifacts. We hypothesize that hematoma volume measurement on QSM is independent of imaging parameters, eliminating its echo time dependence on gradient echo MRI. METHODS-: Gradient echo MRI of 16 patients with intracerebral hemorrhage was processed with susceptibility-weighted imaging, R* (=1/T2*) mapping, and QSM at various echo times. Hematoma volumes were measured from these images. RESULTS-: Linear regression of hematoma volume versus echo time showed substantial slopes for gradient echo magnitude (0.45±0.31 L/s), susceptibility-weighted imaging (0.52±0.46), and R* (0.39±0.30) but nearly zero slope for QSM (0.01±0.05). At echo time=20 ms, hematoma volume on QSM was 0.80× that on gradient echo magnitude image (R2=0.99). CONCLUSIONS-: QSM can provide reliable measurement of hematoma volume, which can be performed rapidly and accurately using a semiautomated segmentation tool.
KW - gradient echo
KW - hematoma volume
KW - intracerebral hemorrhage
KW - magnetic resonance imaging
KW - quantitative susceptibility mapping
UR - http://www.scopus.com/inward/record.url?scp=84880782618&partnerID=8YFLogxK
U2 - 10.1161/STROKEAHA.113.001638
DO - 10.1161/STROKEAHA.113.001638
M3 - Article
C2 - 23704111
AN - SCOPUS:84880782618
SN - 0039-2499
VL - 44
SP - 2315
EP - 2317
JO - Stroke
JF - Stroke
IS - 8
ER -