Glucose regulation for subjects with type 1 diabetes using active disturbance rejection control

Deheng Cai, Jiliang Song, Junzheng Wang, Dawei Shi*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

7 Citations (Scopus)

Abstract

In artificial pancreas (AP) systems, control algorithms play an important role in the blood glucose (BG) regulation. The ability of active disturbance rejection control (ADRC), which can deal with various disturbances, enables it to become a promising approach in the control algorithm design for BG regulation when facing many disturbances (e.g. glucose fluctuation caused by meal intakes and exercises). In this paper, an ADRC controller is proposed for the AP systems. To ensure the safety, the insulin on board (IOB) constraints and the insulin delivery constraints are introduced to the ADRC controller. The controller is evaluated on the FDA-accepted UVA/Padova TIDM simulator with the 10-adult cohort. For both announced and unannounced meals, the controller achieves satisfactory performance in terms of mean glucose (139.9 mg/dl for announced meals, 157.9 mg/dl for unannounced meals) and percentage time in [70, 180] mg/dl (91.5% for announced meal, 68.9% for unannounced meals) without having the risk of hypoglycemia.

Original languageEnglish
Title of host publicationProceedings of the 38th Chinese Control Conference, CCC 2019
EditorsMinyue Fu, Jian Sun
PublisherIEEE Computer Society
Pages6970-6975
Number of pages6
ISBN (Electronic)9789881563972
DOIs
Publication statusPublished - Jul 2019
Event38th Chinese Control Conference, CCC 2019 - Guangzhou, China
Duration: 27 Jul 201930 Jul 2019

Publication series

NameChinese Control Conference, CCC
Volume2019-July
ISSN (Print)1934-1768
ISSN (Electronic)2161-2927

Conference

Conference38th Chinese Control Conference, CCC 2019
Country/TerritoryChina
CityGuangzhou
Period27/07/1930/07/19

Keywords

  • Active Disturbance Rejection Control
  • Artificial Pancreas
  • Glucose Regulation
  • Type 1 Diabetes

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