Abstract
In this paper, we study the application of a pulse vaccination strategy to eradicate hepatitis B and C modeled by SIV epidemic model. Since infection age is an important factor of hepatitis progression, we incorporate the infection age into the model. In this model, we consider the infectiousness of latent individuals. We derive the condition in which eradication solution is a global attractor, this condition depends on pulse vaccination proportion p and interpulse time T. We also obtain the condition of the global asymptotic stability of the solution. The condition shows that large enough pulse vaccination proportion and relatively small interpulse time lead to the eradication of hepatitis B and C. Moreover the results of the theoretical study might be instructive to the epidemiology of HIV.
Original language | English |
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Pages (from-to) | 43-51 |
Number of pages | 9 |
Journal | Journal of Biological Systems |
Volume | 14 |
Issue number | 1 |
DOIs | |
Publication status | Published - Mar 2006 |
Keywords
- Epidemic Model
- Global Asymptotic Stability
- Global Attractor
- Impulsive Vaccination
- Infection Age