@inproceedings{db4d38afd04d49eb9ff21025fc0e7188,
title = "Functional network disruption in attention deficit hyperactivity disorder",
abstract = "Recently, many researchers have used graph theory to study the aberrant brain functions in mental disorders. However, the characteristics of the brain functional network in attention deficit hyperactivity disorder (ADHD) are still largely unexplored. In this study, blood oxygen level-dependence (BOLD) functional magnetic resonance images (fMRI) were employed to construct brain functional networks in 57 children with ADHD and 59 healthy controls (HC). The results showed that both groups had similar global efficiency and the ADHD group had significantly decreased local efficiency compared with the HC. The between-group differences of degree values were found in the frontal cortex, temporal cortex and the default mode network (DMN). The ADHD group retained most of the hub regions found in the HC, but showed altered hub regions in the left posterior cingulate gyrus and the right lingual gyrus. This altered topological organization of the functional network might be associated with the underlying pathophysiology in ADHD.",
author = "Zhijun Yao and Bin Hu and Yuanwei Xie and Wei Wang and Ruiyue Liu and Chuanjiang Liang and Yun Su",
note = "Publisher Copyright: {\textcopyright} 2014 IEEE.; 2014 IEEE International Conference on Bioinformatics and Biomedicine, IEEE BIBM 2014 ; Conference date: 02-11-2014 Through 05-11-2014",
year = "2014",
month = dec,
day = "29",
doi = "10.1109/BIBM.2014.6999273",
language = "English",
series = "Proceedings - 2014 IEEE International Conference on Bioinformatics and Biomedicine, IEEE BIBM 2014",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "84--90",
editor = "Huiru Zheng and Hu, {Xiaohua Tony} and Daniel Berrar and Yadong Wang and Werner Dubitzky and Jin-Kao Hao and Kwang-Hyun Cho and David Gilbert",
booktitle = "Proceedings - 2014 IEEE International Conference on Bioinformatics and Biomedicine, IEEE BIBM 2014",
address = "United States",
}