Facile synthesis of magnetic homochiral metal-organic frameworks for "enantioselective fishing"

Cui Lan Chang, Xiao Yue Qi, Jiang Wei Zhang, Ya Ming Qiu, Xian Jiang Li, Xin Wang, Yu Bai, Jun Liang Sun, Hu Wei Liu*

*Corresponding author for this work

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Abstract

Magnetic functionalized homochiral metal-organic frameworks (MOFs) were prepared and applied to efficient enantioselective fishing of chiral drug intermediates. Under optimized conditions, the enantiomeric excess (ee) value as high as 85.2% was achieved for methyl phenyl sulfoxide (MPS) within 3 min.

Original languageEnglish
Pages (from-to)3566-3569
Number of pages4
JournalChemical Communications
Volume51
Issue number17
DOIs
Publication statusPublished - 28 Feb 2015
Externally publishedYes

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Chang, C. L., Qi, X. Y., Zhang, J. W., Qiu, Y. M., Li, X. J., Wang, X., Bai, Y., Sun, J. L., & Liu, H. W. (2015). Facile synthesis of magnetic homochiral metal-organic frameworks for "enantioselective fishing". Chemical Communications, 51(17), 3566-3569. https://doi.org/10.1039/c4cc09988e